1CWD
HUMAN P56LCK TYROSINE KINASE COMPLEXED WITH PHOSPHOPEPTIDE
Summary for 1CWD
| Entry DOI | 10.2210/pdb1cwd/pdb |
| Descriptor | P56LCK TYROSINE KINASE, (PHOSPHONOMETHYL)PHENYLALANINE-CONTAINING PEPTIDE PRO-GLU-GLY-ASP-PM3-GLU-GLU-VAL-LEU (3 entities in total) |
| Functional Keywords | phosphotransferase, complex (phosphotransferase-peptide), phosphotransferase-transferase inhibitor complex, phosphotransferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P06239 |
| Total number of polymer chains | 2 |
| Total formula weight | 12262.48 |
| Authors | Mikol, V. (deposition date: 1995-09-06, release date: 1996-12-07, Last modification date: 2011-07-13) |
| Primary citation | Mikol, V.,Baumann, G.,Keller, T.H.,Manning, U.,Zurini, M.G. The crystal structures of the SH2 domain of p56lck complexed with two phosphopeptides suggest a gated peptide binding site. J.Mol.Biol., 246:344-355, 1995 Cited by PubMed: 7532720DOI: 10.1006/jmbi.1994.0089 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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