1CWD

HUMAN P56LCK TYROSINE KINASE COMPLEXED WITH PHOSPHOPEPTIDE

1CWD の概要

• エントリーDOI: 10.2210/pdb1cwd/pdb
• 分子名称: P56LCK TYROSINE KINASE, (PHOSPHONOMETHYL)PHENYLALANINE-CONTAINING PEPTIDE PRO-GLU-GLY-ASP-PM3-GLU-GLU-VAL-LEU (3 entities in total)
• 機能のキーワード: phosphotransferase, complex (phosphotransferase-peptide), phosphotransferase-transferase inhibitor complex, phosphotransferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P06239
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 12262.48

構造登録者

Mikol, V. (登録日: 1995-09-06, 公開日: 1996-12-07, 最終更新日: 2024-06-05)

• 主引用文献: Mikol, V.,Baumann, G.,Keller, T.H.,Manning, U.,Zurini, M.G.; The crystal structures of the SH2 domain of p56lck complexed with two phosphopeptides suggest a gated peptide binding site.; J.Mol.Biol., 246:344-355, 1995; PubMed: 7532720; DOI: 10.1006/jmbi.1994.0089

実験手法

X-RAY DIFFRACTION (2.25 Å)