1CUL

COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH 2',5'-DIDEOXY-ADENOSINE 3'-TRIPHOSPHATE AND MG

1CUL の概要

• エントリーDOI: 10.2210/pdb1cul/pdb
• 関連するPDBエントリー: 1CS4
• 分子名称: TYPE V ADENYLYL CYCLASE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, TYPE II ADENYLYL CYCLASE, ... (11 entities in total)
• 機能のキーワード: complex (lyase-hydrolase), hydrolase, signal transducing protein, cyclase, effector enzyme, lyase-hydrolase complex, lyase/lyase/signaling protein, lyase-lyase-signaling protein complex
• 由来する生物種: Canis lupus familiaris (dog); 詳細
• 細胞内の位置: Membrane; Multi-pass membrane protein: P30803 P26769; Cell membrane; Lipid-anchor (By similarity): P04896
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 94123.15

構造登録者

Tesmer, J.J.G.,Dessauer, C.A.,Sunahara, R.K.,Johnson, R.A.,Gilman, A.G.,Sprang, S.R. (登録日: 1999-08-20, 公開日: 2001-01-10, 最終更新日: 2024-02-07)

• 主引用文献: Tesmer, J.J.,Dessauer, C.W.,Sunahara, R.K.,Murray, L.D.,Johnson, R.A.,Gilman, A.G.,Sprang, S.R.; Molecular basis for P-site inhibition of adenylyl cyclase.; Biochemistry, 39:14464-14471, 2000; PubMed: 11087399; DOI: 10.1021/bi0015562

実験手法

X-RAY DIFFRACTION (2.4 Å)