1CSB
Crystal structure of cathepsin b inhibited with CA030 at 2.1 angstroms resolution: A basis for the design of specific epoxysuccinyl inhibitors
Summary for 1CSB
Entry DOI | 10.2210/pdb1csb/pdb |
Related PRD ID | PRD_000310 |
Descriptor | CATHEPSIN B light chain, CATHEPSIN B heavy chain, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-isoleucyl-L-proline, ... (4 entities in total) |
Functional Keywords | papain-like lysosomal dicarboxy-peptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Lysosome: P07858 P07858 |
Total number of polymer chains | 4 |
Total formula weight | 56048.33 |
Authors | |
Primary citation | Turk, D.,Podobnik, M.,Popovic, T.,Katunuma, N.,Bode, W.,Huber, R.,Turk, V. Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors. Biochemistry, 34:4791-4797, 1995 Cited by PubMed: 7718586DOI: 10.1021/bi00014a037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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