1CPI

REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES. DESIGN OF HYDROLYTICALLY STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE

Summary for 1CPI

• Entry DOI: 10.2210/pdb1cpi/pdb
• Related PRD ID: PRD_000407
• Descriptor: HIV-1 PROTEASE, CYCLIC PEPTIDE INHIBITOR, SULFATE ION, ... (4 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03369
• Total number of polymer chains: 3
• Total formula weight: 22585.19

Authors

Martin, J.L. (deposition date: 1995-10-16, release date: 1996-03-08, Last modification date: 2012-12-12)

• Primary citation: Abbenante, G.,March, D.R.,Bergman, D.A.,Hunt, P.A.,Garnham, B.,Dancer, R.J.,Martin, J.L.,Fairlie, D.P.; REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES - DESIGN OF HYDROLYTICALLY-STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE.; J.Am.Chem.Soc., 117:10220-10226, 1995

Experimental method

X-RAY DIFFRACTION (2.05 Å)