1CPI

REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES. DESIGN OF HYDROLYTICALLY STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE

1CPI の概要

• エントリーDOI: 10.2210/pdb1cpi/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000407
• 分子名称: HIV-1 PROTEASE, CYCLIC PEPTIDE INHIBITOR, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03369
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 22585.19

構造登録者

Martin, J.L. (登録日: 1995-10-16, 公開日: 1996-03-08, 最終更新日: 2024-06-05)

• 主引用文献: Abbenante, G.,March, D.R.,Bergman, D.A.,Hunt, P.A.,Garnham, B.,Dancer, R.J.,Martin, J.L.,Fairlie, D.P.; REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES - DESIGN OF HYDROLYTICALLY-STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE.; J.Am.Chem.Soc., 117:10220-10226, 1995

実験手法

X-RAY DIFFRACTION (2.05 Å)