1CG1

STRUCTURE OF THE MUTANT (K16Q) OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH HADACIDIN, GDP, 6-PHOSPHORYL-IMP, AND MG2+

Summary for 1CG1

Entry DOI	10.2210/pdb1cg1/pdb
Descriptor	PROTEIN (ADENYLOSUCCINATE SYNTHETASE), MAGNESIUM ION, HADACIDIN, ... (6 entities in total)
Functional Keywords	ligase, gtp-hydrolysing enzymes, purine 2 nucleotide biosynthesis, 6-phosporyl-imp
Biological source	Escherichia coli K12
Cellular location	Cytoplasm: P0A7D4
Total number of polymer chains	1
Total formula weight	48283.32
Authors	Choe, J.Y.,Poland, B.W.,Fromm, H.,Honzatko, R. (deposition date: 1999-03-26, release date: 1999-06-17, Last modification date: 2023-08-09)
Primary citation	Choe, J.Y.,Poland, B.W.,Fromm, H.J.,Honzatko, R.B. Mechanistic implications from crystalline complexes of wild-type and mutant adenylosuccinate synthetases from Escherichia coli. Biochemistry, 38:6953-6961, 1999 Cited by PubMed: 10346917 DOI: 10.1021/bi990159s PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation