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1CAQ

X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXES WITH NON-PEPTIDE INHIBITORS: IMPLICATION FOR INHIBITOR SELECTIVITY

Summary for 1CAQ
Entry DOI10.2210/pdb1caq/pdb
DescriptorPROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ... (6 entities in total)
Functional Keywordsmatrix metalloproteinase, mmp-3, non-peptide inhibitor, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space, extracellular matrix : P08254
Total number of polymer chains1
Total formula weight19737.76
Authors
Pavlovsky, A.G.,Williams, M.G.,Ye, Q.-Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L. (deposition date: 1999-02-23, release date: 1999-07-07, Last modification date: 2023-12-27)
Primary citationPavlovsky, A.G.,Williams, M.G.,Ye, Q.Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L.
X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.
Protein Sci., 8:1455-1462, 1999
Cited by
PubMed: 10422833
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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