1C7U

Complex of the DNA binding core domain of the transcription factor MEF2A with a 20mer oligonucleotide

Summary for 1C7U

Descriptor5'-D(*CP*TP*CP*GP*GP*CP*TP*AP*TP*TP*AP*AP*TP*AP*GP*CP*CP*GP*AP*G)-3', MYOCYTE-SPECIFIC ENHANCER FACTOR 2A, C4 FORM (2 entities in total)
Functional Keywordsdna binding protein, transcription factor, mads-box, sam domain, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q02078
Total number of polymer chains4
Total molecular weight32282.93
Authors
Clore, G.M.,Huang, K. (deposition date: 2000-03-17, release date: 2000-03-27, Last modification date: 2011-07-13)
Primary citation
Huang, K.,Louis, J.M.,Donaldson, L.,Lim, F.L.,Sharrocks, A.D.,Clore, G.M.
Solution structure of the MEF2A-DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factors
Embo J., 19:2615-2628, 2000
PubMed: 10835359 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/19.11.2615
MImport into Mendeley
Experimental method
SOLUTION NMR
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers18 1.4% 11.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload
171588
PDB entries from 2020-11-25