1C6V

SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H)

Summary for 1C6V

Entry DOI	10.2210/pdb1c6v/pdb
Descriptor	PROTEIN (SIV INTEGRASE), PROTEIN (SIU89134) (3 entities in total)
Functional Keywords	dna integration, dna binding protein
Biological source	Simian immunodeficiency virus More
Total number of polymer chains	5
Total formula weight	82809.31
Authors	Chen, Z.,Yan, Y.,Munshi, S.,Li, Y.,Zruygay-Murphy, J.,Xu, B.,Witmer, M.,Felock, P.,Wolfe, A.,Sardana, V.,Emini, E.A.,Hazuda, D.,Kuo, L.C. (deposition date: 1999-12-21, release date: 2000-12-27, Last modification date: 2023-08-09)
Primary citation	Chen, Z.,Yan, Y.,Munshi, S.,Li, Y.,Zugay-Murphy, J.,Xu, B.,Witmer, M.,Felock, P.,Wolfe, A.,Sardana, V.,Emini, E.A.,Hazuda, D.,Kuo, L.C. X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform. J.Mol.Biol., 296:521-533, 2000 Cited by PubMed: 10669606 DOI: 10.1006/jmbi.1999.3451 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation