1C3V

DIHYDRODIPICOLINATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND PDC

Summary for 1C3V

• Entry DOI: 10.2210/pdb1c3v/pdb
• Related: 1P9L
• Descriptor: DIHYDRODIPICOLINATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PYRIDINE-2,6-DICARBOXYLIC ACID, ... (5 entities in total)
• Functional Keywords: two-domain structure, tb structural genomics consortium, tbsgc, structural genomics, psi, protein structure initiative, oxidoreductase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 53606.07

Authors

Cirilli, M.,Zheng, R.,Scapin, G.,Blanchard, J.S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 1999-07-28, release date: 2003-08-26, Last modification date: 2024-02-07)

• Primary citation: Cirilli, M.,Zheng, R.,Scapin, G.,Blanchard, J.S.; The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity; Biochemistry, 42:10644-10650, 2003; PubMed: 12962488; DOI: 10.1021/bi030044v

Experimental method

X-RAY DIFFRACTION (2.39 Å)