1C3V

DIHYDRODIPICOLINATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND PDC

1C3V の概要

• エントリーDOI: 10.2210/pdb1c3v/pdb
• 関連するPDBエントリー: 1P9L
• 分子名称: DIHYDRODIPICOLINATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PYRIDINE-2,6-DICARBOXYLIC ACID, ... (5 entities in total)
• 機能のキーワード: two-domain structure, tb structural genomics consortium, tbsgc, structural genomics, psi, protein structure initiative, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53606.07

構造登録者

Cirilli, M.,Zheng, R.,Scapin, G.,Blanchard, J.S.,TB Structural Genomics Consortium (TBSGC) (登録日: 1999-07-28, 公開日: 2003-08-26, 最終更新日: 2024-02-07)

• 主引用文献: Cirilli, M.,Zheng, R.,Scapin, G.,Blanchard, J.S.; The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity; Biochemistry, 42:10644-10650, 2003; PubMed: 12962488; DOI: 10.1021/bi030044v

実験手法

X-RAY DIFFRACTION (2.39 Å)