1BZS

CRYSTAL STRUCTURE OF MMP8 COMPLEXED WITH HMR2909

Summary for 1BZS

Entry DOI	10.2210/pdb1bzs/pdb
Descriptor	NEUTROPHIL COLLAGENASE, CALCIUM ION, ZINC ION, ... (6 entities in total)
Functional Keywords	metallo proteinase, hydroxamate, matrix degradation, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasmic granule: P22894
Total number of polymer chains	1
Total formula weight	19216.74
Authors	Schreuder, H.,Brachvogel, V.,Loenze, P. (deposition date: 1998-11-04, release date: 2000-05-31, Last modification date: 2023-08-09)
Primary citation	Matter, H.,Schwab, W.,Barbier, D.,Billen, G.,Haase, B.,Neises, B.,Schudok, M.,Thorwart, W.,Schreuder, H.,Brachvogel, V.,Lonze, P.,Weithmann, K.U. Quantitative structure-activity relationship of human neutrophil collagenase (MMP-8) inhibitors using comparative molecular field analysis and X-ray structure analysis. J.Med.Chem., 42:1908-1920, 1999 Cited by PubMed: 10354399 DOI: 10.1021/jm980631s PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation