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1BO7

THYMIDYLATE SYNTHASE R179T MUTANT

Summary for 1BO7
Entry DOI10.2210/pdb1bo7/pdb
DescriptorPROTEIN (THYMIDYLATE SYNTHASE), URIDINE-5'-MONOPHOSPHATE (3 entities in total)
Functional Keywordstransferase (methyltransferase), transferase, methyltransferase, nucleotide biosynthesis
Biological sourceLactobacillus casei
Cellular locationCytoplasm: P00469
Total number of polymer chains1
Total formula weight36898.54
Authors
Morse, R.,Finer-Moore, J.,Stroud, R.M. (deposition date: 1998-08-10, release date: 1998-08-19, Last modification date: 2023-08-09)
Primary citationMorse, R.J.,Kawase, S.,Santi, D.V.,Finer-Moore, J.,Stroud, R.M.
Energetic contributions of four arginines to phosphate-binding in thymidylate synthase are more than additive and depend on optimization of "effective charge balance".
Biochemistry, 39:1011-1020, 2000
Cited by
PubMed: 10653645
DOI: 10.1021/bi9918590
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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