1BMW

A fibronectin type III fold in plant allergens: The solution structure of Phl PII from timothy grass pollen, NMR, 38 STRUCTURES

Summary for 1BMW

• Entry DOI: 10.2210/pdb1bmw/pdb
• Descriptor: POLLEN ALLERGEN PHL P2 (1 entity in total)
• Functional Keywords: allergen, allergy, immunoglobulins, immunology
• Biological source: Phleum pratense (timothy grass)
• Total number of polymer chains: 1
• Total formula weight: 10828.06

Authors

De Marino, S.,Morelli, M.A.C.,Fraternali, F.,Tamborino, E.,Vrtala, S.,Dolecek, C.,Arosio, P.,Valenta, R.,Pastore, A. (deposition date: 1998-07-27, release date: 1999-01-13, Last modification date: 2024-05-22)

Primary citation

De Marino, S.,Morelli, M.A.,Fraternali, F.,Tamborino, E.,Vrtala, S.,Dolocek, C.,Arosio, P.,Valenta, R.,Pastore, A.
An Immunoglobulin-Like Fold in a Major Plant Allergen: The Solution Structure of Phl P 2 from Timothy Grass Pollen.
Structure Fold.Des., 7:943-952, 1999

PubMed Abstract: Grass pollen allergens are the most important and widespread elicitors of pollen allergy. One of the major plant allergens which millions of people worldwide are sensitized to is Phl p 2, a small protein from timothy grass pollen. Phl p 2 is representative of the large family of cross-reacting plant allergens classified as group 2/3. Recombinant Phl p 2 has been demonstrated by immunological cross-reactivity studies to be immunologically equivalent to the natural protein.

PubMed: 10467147
DOI: 10.1016/S0969-2126(99)80121-X

Experimental method

SOLUTION NMR