1BKM
COCRYSTAL STRUCTURE OF D-AMINO ACID SUBSTITUTED PHOSPHOPEPTIDE COMPLEX
Summary for 1BKM
Entry DOI | 10.2210/pdb1bkm/pdb |
Descriptor | PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN, [[O-PHOSPHONO-N-ACETYL-TYROSINYL]-GLUTAMYL-3[CYCLOHEXYLMETHYL]ALANINYL]-AMINE (3 entities in total) |
Functional Keywords | v-src sh2 domain, phosphotyrosine recognition domain, pp60 src sh2 domain, tripeptide, d-amino acid, transforming protein |
Biological source | Rous sarcoma virus |
Total number of polymer chains | 1 |
Total formula weight | 13419.97 |
Authors | Holland, D.R.,Rubin, J.R. (deposition date: 1997-05-02, release date: 1997-07-07, Last modification date: 2024-05-22) |
Primary citation | Holland, D.R.,Lunney, E.A.,Plummer, M.S.,Mueller, W.T.,Mcconnell, P.,Pavlovsky, A.,Para, K.S.,Shahripour, A.,Humblet, C.,Sawyer, T.K.,Rubin, J.R. Structure-Based Design of a Novel Series of Nonpeptide Ligands that Bind to the Pp60Src Sh2 Domain J.Am.Chem.Soc., 119:12471-, 1997 Cited by |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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