1BKM

COCRYSTAL STRUCTURE OF D-AMINO ACID SUBSTITUTED PHOSPHOPEPTIDE COMPLEX

Summary for 1BKM

DescriptorPP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN, [[O-PHOSPHONO-N-ACETYL-TYROSINYL]-GLUTAMYL-3[CYCLOHEXYLMETHYL]ALANINYL]-AMINE (3 entities in total)
Functional Keywordsv-src sh2 domain, phosphotyrosine recognition domain, pp60 src sh2 domain, tripeptide, d-amino acid, transforming protein
Biological sourceRous sarcoma virus
Total number of polymer chains1
Total molecular weight13419.97
Authors
Holland, D.R.,Rubin, J.R. (deposition date: 1997-05-02, release date: 1997-07-07, Last modification date: 2011-07-13)
Primary citation
Holland, D.R.,Lunney, E.A.,Plummer, M.S.,Mueller, W.T.,Mcconnell, P.,Pavlovsky, A.,Para, K.S.,Shahripour, A.,Humblet, C.,Sawyer, T.K.,Rubin, J.R.
Structure-Based Design of a Novel Series of Nonpeptide Ligands that Bind to the Pp60Src Sh2 Domain
J.Am.Chem.Soc., 119:12471-, 1997
Experimental method
X-RAY DIFFRACTION (2 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers8014.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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