1BIX
THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES
Summary for 1BIX
Entry DOI | 10.2210/pdb1bix/pdb |
Descriptor | AP ENDONUCLEASE 1, SAMARIUM (III) ION, PLATINUM (II) ION, ... (4 entities in total) |
Functional Keywords | dna repair, endonuclease, hap1, ref-1, abasic site recognition |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus. DNA-(apurinic or apyrimidinic site) lyase, mitochondrial: Mitochondrion: P27695 |
Total number of polymer chains | 1 |
Total formula weight | 33084.20 |
Authors | Gorman, M.A.,Morera, S.,Rothwell, D.G.,De La Fortelle, E.,Mol, C.D.,Tainer, J.A.,Hickson, I.D.,Freemont, P.S. (deposition date: 1998-06-19, release date: 1999-06-22, Last modification date: 2024-02-07) |
Primary citation | Gorman, M.A.,Morera, S.,Rothwell, D.G.,de La Fortelle, E.,Mol, C.D.,Tainer, J.A.,Hickson, I.D.,Freemont, P.S. The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. EMBO J., 16:6548-6558, 1997 Cited by PubMed: 9351835DOI: 10.1093/emboj/16.21.6548 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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