1BHF

P56LCK SH2 DOMAIN INHIBITOR COMPLEX

Summary for 1BHF

• Entry DOI: 10.2210/pdb1bhf/pdb
• Related PRD ID: PRD_000406
• Descriptor: T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK, INHIBITOR ACE-IPA-GLU-GLU-ILE (3 entities in total)
• Functional Keywords: sh2 domain, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P06239
• Total number of polymer chains: 2
• Total formula weight: 12878.28

Authors

Tong, L.,Warren, T.C.,Lukas, S.,Schembri-King, J.,Betageri, R.,Proudfoot, J.R.,Jakes, S. (deposition date: 1998-06-08, release date: 1998-10-21, Last modification date: 2012-12-12)

• Primary citation: Tong, L.,Warren, T.C.,Lukas, S.,Schembri-King, J.,Betageri, R.,Proudfoot, J.R.,Jakes, S.; Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding.; J.Biol.Chem., 273:20238-20242, 1998; PubMed: 9685372; DOI: 10.1074/jbc.273.32.20238

Experimental method

X-RAY DIFFRACTION (1.8 Å)