1BHF
P56LCK SH2 DOMAIN INHIBITOR COMPLEX
Summary for 1BHF
Entry DOI | 10.2210/pdb1bhf/pdb |
Related PRD ID | PRD_000406 |
Descriptor | T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK, INHIBITOR ACE-IPA-GLU-GLU-ILE (3 entities in total) |
Functional Keywords | sh2 domain, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P06239 |
Total number of polymer chains | 2 |
Total formula weight | 12878.28 |
Authors | Tong, L.,Warren, T.C.,Lukas, S.,Schembri-King, J.,Betageri, R.,Proudfoot, J.R.,Jakes, S. (deposition date: 1998-06-08, release date: 1998-10-21, Last modification date: 2024-06-05) |
Primary citation | Tong, L.,Warren, T.C.,Lukas, S.,Schembri-King, J.,Betageri, R.,Proudfoot, J.R.,Jakes, S. Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding. J.Biol.Chem., 273:20238-20242, 1998 Cited by PubMed: 9685372DOI: 10.1074/jbc.273.32.20238 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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