1BC8
STRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS
Summary for 1BC8
Entry DOI | 10.2210/pdb1bc8/pdb |
Descriptor | DNA (5'-D(*TP*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), DNA (5'-D(*AP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), PROTEIN (SAP-1 ETS DOMAIN), ... (5 entities in total) |
Functional Keywords | ets domain, dna-binding domain, winged helix-turn-helix, dna-binding specificity, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P28324 |
Total number of polymer chains | 3 |
Total formula weight | 17439.04 |
Authors | Mo, Y.,Vaessen, B.,Johnston, K.,Marmorstein, R. (deposition date: 1998-05-05, release date: 1998-12-01, Last modification date: 2024-02-07) |
Primary citation | Mo, Y.,Vaessen, B.,Johnston, K.,Marmorstein, R. Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins. Mol.Cell, 2:201-212, 1998 Cited by PubMed: 9734357DOI: 10.1016/S1097-2765(00)80130-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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