1B8X

GLUTATHIONE S-TRANSFERASE FUSED WITH THE NUCLEAR MATRIX TARGETING SIGNAL OF THE TRANSCRIPTION FACTOR AML-1

Summary for 1B8X

Entry DOI	10.2210/pdb1b8x/pdb
Descriptor	PROTEIN (AML-1B) (1 entity in total)
Functional Keywords	nuclear matrix targeting signal protein, signal protein
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	32124.12
Authors	Tang, L.,Guo, B.,Van Wijnen, A.J.,Lian, J.B.,Stein, J.L.,Stein, G.S.,Zhou, G.W. (deposition date: 1999-02-03, release date: 1999-04-12, Last modification date: 2023-08-09)
Primary citation	Tang, L.,Guo, B.,van Wijnen, A.J.,Lian, J.B.,Stein, J.L.,Stein, G.S.,Zhou, G.W. Preliminary crystallographic study of glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription factor AML-1/CBF-alpha2. J.Struct.Biol., 123:83-85, 1998 Cited by PubMed Abstract: A glutathione S-transferase fused with the nuclear matrix targeting signal (GST-NMTS) of AML-1/CBF-alpha2 has been crystallized by the vapor diffusion method using polyethylene glycol (PEG) as the precipitant. The NMTS is a 31-amino-acid signal peptide that can target the AML-1/CBF-alpha2 protein to the nuclear matrix. The crystal belongs to tetragonal space group P43212 with unit cell dimensions a = b = 93.4 A, c = 57.6 A. There is one GST-fusion protein per asymmetric unit. Crystals diffracted to at least 2.7 A and are appropriate for structure determination. PubMed: 9774548 DOI: 10.1006/jsbi.1998.4016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation