1B6A

HUMAN METHIONINE AMINOPEPTIDASE 2 COMPLEXED WITH TNP-470

Summary for 1B6A

• Entry DOI: 10.2210/pdb1b6a/pdb
• Descriptor: METHIONINE AMINOPEPTIDASE, COBALT (II) ION, (1R,2S,3S,4R)-4-hydroxy-2-methoxy-4-methyl-3-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]cyclohexyl (chloroacetyl)carbamate, ... (4 entities in total)
• Functional Keywords: angiogenesis inhibitor, aminopeptidase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 53493.29

Authors

Liu, S.,Clardy, J.C. (deposition date: 1999-01-13, release date: 2000-01-13, Last modification date: 2023-08-02)

• Primary citation: Liu, S.,Widom, J.,Kemp, C.W.,Crews, C.M.,Clardy, J.; Structure of human methionine aminopeptidase-2 complexed with fumagillin.; Science, 282:1324-1327, 1998; PubMed: 9812898; DOI: 10.1126/science.282.5392.1324

Experimental method

X-RAY DIFFRACTION (1.6 Å)