1B3O

TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE

Summary for 1B3O

• Entry DOI: 10.2210/pdb1b3o/pdb
• Descriptor: PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ... (5 entities in total)
• Functional Keywords: dehydrogenase, impd, impdh, guanine nucleotide synthesis
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 113917.74

Authors

Colby, T.D.,Vanderveen, K.,Strickler, M.D.,Goldstein, B.M. (deposition date: 1998-12-14, release date: 1999-04-12, Last modification date: 2024-04-03)

• Primary citation: Colby, T.D.,Vanderveen, K.,Strickler, M.D.,Markham, G.D.,Goldstein, B.M.; Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.; Proc.Natl.Acad.Sci.USA, 96:3531-3536, 1999; PubMed: 10097070; DOI: 10.1073/pnas.96.7.3531

Experimental method

X-RAY DIFFRACTION (2.9 Å)