1AUK

HUMAN ARYLSULFATASE A

Summary for 1AUK

Entry DOI	10.2210/pdb1auk/pdb
Descriptor	ARYLSULFATASE A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	cerebroside-3-sulfate hydrolysis, lysosomal enzyme, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Lysosome: P15289
Total number of polymer chains	1
Total formula weight	52405.44
Authors	Lukatela, G.,Krauss, N.,Theis, K.,Gieselmann, V.,Von Figura, K.,Saenger, W. (deposition date: 1997-08-29, release date: 1998-03-04, Last modification date: 2020-07-29)
Primary citation	Lukatela, G.,Krauss, N.,Theis, K.,Selmer, T.,Gieselmann, V.,von Figura, K.,Saenger, W. Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis. Biochemistry, 37:3654-3664, 1998 Cited by PubMed: 9521684 DOI: 10.1021/bi9714924 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation