1AUI

HUMAN CALCINEURIN HETERODIMER

Summary for 1AUI

Entry DOI	10.2210/pdb1aui/pdb
Descriptor	SERINE/THREONINE PHOSPHATASE 2B, ZINC ION, FE (III) ION, ... (6 entities in total)
Functional Keywords	hydrolase, phosphatase, immunosuppression
Biological source	Homo sapiens (human) More
Cellular location	Nucleus (By similarity): Q08209
Total number of polymer chains	2
Total formula weight	78229.95
Authors	Kissinger, C.R.,Parge, H.E.,Knighton, D.R.,Pelletier, L.A.,Lewis, C.T.,Tempczyk, A.,Villafranca, J.E. (deposition date: 1997-08-27, release date: 1997-12-03, Last modification date: 2024-02-07)
Primary citation	Kissinger, C.R.,Parge, H.E.,Knighton, D.R.,Lewis, C.T.,Pelletier, L.A.,Tempczyk, A.,Kalish, V.J.,Tucker, K.D.,Showalter, R.E.,Moomaw, E.W.,Gastinel, L.N.,Habuka, N.,Chen, X.,Maldonado, F.,Barker, J.E.,Bacquet, R.,Villafranca, J.E. Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex. Nature, 378:641-644, 1995 Cited by PubMed: 8524402 DOI: 10.1038/378641a0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation