1AP1

THE SOLUTION NMR STRUCTURE OF AN S-STYRENE OXIDE ADDUCT AT THE N2 POSITION OF GUANINE OF AN 11 BASE-PAIR OLIGONUCLEOTIDE SEQUENCE CODING FOR AMINO ACIDS 11-13 OF THE PRODUCT OF THE N-RAS PROTOONCOGENE, MINIMIZED AVERAGE STRUCTURE

Summary for 1AP1

• Entry DOI: 10.2210/pdb1ap1/pdb
• Descriptor: DNA (5'-D(*GP*GP*CP*AP*GSSP*GP*TP*GP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*CP*AP*CP*CP*TP*GP*CP*C)-3') (2 entities in total)
• Functional Keywords: dna duplex, human n-ras gene, codon 12 sequence, s-styrene oxide, minor groove adduct, deoxyribonucleic acid, dna
• Total number of polymer chains: 2
• Total formula weight: 6829.53

Authors

Setayesh, F.R.,Stone, M.P. (deposition date: 1997-07-22, release date: 1998-07-22, Last modification date: 2022-02-16)

• Primary citation: Setayesh, F.R.,DeCorte, B.L.,Horton, P.,Harris, C.M.,Harris, T.M.,Stone, M.P.; Styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 12: minor groove structures of the R(12,1)- and S(12,1)-alpha-(N2-guanyl) stereoisomers determined by 1H nuclear magnetic resonance.; Chem.Res.Toxicol., 11:766-777, 1998; PubMed: 9671539; DOI: 10.1021/tx9800147

Experimental method

SOLUTION NMR