1ALA

STRUCTURE OF CHICKEN ANNEXIN V AT 2.25-ANGSTROMS RESOLUTION

1ALA の概要

• エントリーDOI: 10.2210/pdb1ala/pdb
• 分子名称: ANNEXIN V, CALCIUM ION (3 entities in total)
• 機能のキーワード: calcium/phospholipid-binding protein, calcium-phospholipid-binding protein complex
• 由来する生物種: Gallus gallus (chicken)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36382.59

構造登録者

Waller, D.A.,Bewley, M.C.,Huber, R. (登録日: 1993-01-14, 公開日: 1993-10-31, 最終更新日: 2024-02-07)

主引用文献

Bewley, M.C.,Boustead, C.M.,Walker, J.H.,Waller, D.A.,Huber, R.
Structure of chicken annexin V at 2.25-A resolution.
Biochemistry, 32:3923-3929, 1993

PubMed Abstract: The crystal structure of chicken annexin V has been solved by molecular replacement and refined at 2.25 A. The final R factor is 19.7% with good geometry. The chicken annexin V structure is very similar to the human annexin V structure, with four similar domains each containing five helices. The structure includes three calcium ions in domains I, II, and IV, each bound by the characteristic K-G-X-G-T-(38 residues)-D/E motif. In view of the structural similarity between human and chicken annexin V, we suggest that they have a common vital function which developed early in evolutionary history.

PubMed: 8471604
DOI: 10.1021/bi00066a011

実験手法

X-RAY DIFFRACTION (2.25 Å)