1AKN

STRUCTURE OF BILE-SALT ACTIVATED LIPASE

1AKN の概要

• エントリーDOI: 10.2210/pdb1akn/pdb
• 分子名称: BILE-SALT ACTIVATED LIPASE, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• 機能のキーワード: hydrolase, serine esterase, lipid degradation, glycoprotein, carboxylic esterase, hydrolase()
• 由来する生物種: Bos taurus (cattle)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 63832.57

構造登録者

Wang, X.,Zhang, X. (登録日: 1997-05-23, 公開日: 1998-05-27, 最終更新日: 2024-10-09)

主引用文献

Wang, X.,Wang, C.S.,Tang, J.,Dyda, F.,Zhang, X.C.
The crystal structure of bovine bile salt activated lipase: insights into the bile salt activation mechanism.
Structure, 5:1209-1218, 1997

PubMed Abstract: The intestinally located pancreatic enzyme, bile salt activated lipase (BAL), possesses unique activities for digesting different kinds of lipids. It also differs from other lipases in a requirement of bile salts for activity. A structure-based explanation for these unique properties has not been reached so far due to the absence of a three-dimensional structure.

PubMed: 9331420
DOI: 10.1016/S0969-2126(97)00271-2

実験手法

X-RAY DIFFRACTION (2.8 Å)