1AIQ

CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE R126E MUTANT

Summary for 1AIQ

DescriptorTHYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, ... (4 entities in total)
Functional Keywordstransferase, methyltransferase
Biological sourceEscherichia coli
Cellular locationCytoplasm  P0A884
Total number of polymer chains2
Total molecular weight62634.47
Authors
Strop, P.,Montfort, W.R. (deposition date: 1997-04-23, release date: 1997-11-12, Last modification date: 2018-04-18)
Primary citation
Strop, P.,Changchien, L.,Maley, F.,Montfort, W.R.
Crystal structures of a marginally active thymidylate synthase mutant, Arg 126-->Glu.
Protein Sci., 6:2504-2511, 1997
PubMed: 9416600 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers120.4%11.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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