1AIO
CRYSTAL STRUCTURE OF A DOUBLE-STRANDED DNA CONTAINING THE MAJOR ADDUCT OF THE ANTICANCER DRUG CISPLATIN
Replaces: 1GPGSummary for 1AIO
Entry DOI | 10.2210/pdb1aio/pdb |
Descriptor | DNA (5'-D(*CP*CP*(BRU)P*CP*TP*[PT(NH3)2(GP*GP)]*TP*CP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*GP*AP*CP*CP*AP*GP*AP*GP*G)-3'), Cisplatin, ... (4 entities in total) |
Functional Keywords | right handed dna, double helix, complexed with drug, modified, dna |
Total number of polymer chains | 4 |
Total formula weight | 15383.40 |
Authors | Takahara, P.M.,Rosenzweig, A.C.,Frederick, C.A.,Lippard, S.J. (deposition date: 1997-04-23, release date: 1997-04-24, Last modification date: 2024-02-07) |
Primary citation | Takahara, P.M.,Rosenzweig, A.C.,Frederick, C.A.,Lippard, S.J. Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin. Nature, 377:649-652, 1995 Cited by PubMed: 7566180DOI: 10.1038/377649a0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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