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1AEM

SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (IMIDAZO[1,2-A]PYRIDINE)

Summary for 1AEM
Entry DOI10.2210/pdb1aem/pdb
DescriptorCYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZO[1,2-A]PYRIDINE, ... (4 entities in total)
Functional Keywordsoxidoreductase, peroxidase, transit peptide
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationMitochondrion matrix: P00431
Total number of polymer chains1
Total formula weight34194.87
Authors
Musah, R.A.,Jensen, G.M.,Fitzgerald, M.M.,Mcree, D.E.,Goodin, D.B. (deposition date: 1997-02-25, release date: 1997-09-04, Last modification date: 2023-08-02)
Primary citationMusah, R.A.,Jensen, G.M.,Bunte, S.W.,Rosenfeld, R.J.,Goodin, D.B.
Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315:845-857, 2002
Cited by
PubMed: 11812152
DOI: 10.1006/jmbi.2001.5287
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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