1AE6

IGG-FAB FRAGMENT OF MOUSE MONOCLONAL ANTIBODY CTM01

Summary for 1AE6

• Entry DOI: 10.2210/pdb1ae6/pdb
• Descriptor: IGG CTM01 FAB (LIGHT CHAIN), IGG CTM01 FAB (HEAVY CHAIN) (2 entities in total)
• Functional Keywords: immunoglobulin, fab fragment, humanisation
• Biological source: Mus musculus (house mouse); More
• Cellular location: Cell membrane; Single-pass membrane protein (Potential): P01869
• Total number of polymer chains: 2
• Total formula weight: 47664.26

Authors

Banfield, M.J.,Brady, R.L. (deposition date: 1997-03-06, release date: 1998-03-18, Last modification date: 2023-08-02)

• Primary citation: Banfield, M.J.,King, D.J.,Mountain, A.,Brady, R.L.; VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs.; Proteins, 29:161-171, 1997; PubMed: 9329081; DOI: 10.1002/(SICI)1097-0134(199710)29:2<161::AID-PROT4>3.0.CO;2-G

Experimental method

X-RAY DIFFRACTION (3 Å)