1A85
MMP8 WITH MALONIC AND ASPARAGINE BASED INHIBITOR
Summary for 1A85
Entry DOI | 10.2210/pdb1a85/pdb |
Related PRD ID | PRD_000249 |
Descriptor | MMP-8, CALCIUM ION, ZINC ION, ... (4 entities in total) |
Functional Keywords | collagenase, matrix metalloproteinase, malonic acid, mmp8, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasmic granule: P22894 |
Total number of polymer chains | 1 |
Total formula weight | 18216.53 |
Authors | Brandstetter, H.,Roedern, E.G.V.,Grams, F.,Engh, R.A. (deposition date: 1998-04-03, release date: 1999-04-27, Last modification date: 2024-02-07) |
Primary citation | Brandstetter, H.,Engh, R.A.,Von Roedern, E.G.,Moroder, L.,Huber, R.,Bode, W.,Grams, F. Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data. Protein Sci., 7:1303-1309, 1998 Cited by PubMed: 9655333PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report