1A85

MMP8 WITH MALONIC AND ASPARAGINE BASED INHIBITOR

1A85 の概要

• エントリーDOI: 10.2210/pdb1a85/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000249
• 分子名称: MMP-8, CALCIUM ION, ZINC ION, ... (4 entities in total)
• 機能のキーワード: collagenase, matrix metalloproteinase, malonic acid, mmp8, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasmic granule: P22894
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18216.53

構造登録者

Brandstetter, H.,Roedern, E.G.V.,Grams, F.,Engh, R.A. (登録日: 1998-04-03, 公開日: 1999-04-27, 最終更新日: 2024-02-07)

• 主引用文献: Brandstetter, H.,Engh, R.A.,Von Roedern, E.G.,Moroder, L.,Huber, R.,Bode, W.,Grams, F.; Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data.; Protein Sci., 7:1303-1309, 1998; PubMed: 9655333

実験手法

X-RAY DIFFRACTION (2 Å)