Summary for 1A35
| Descriptor | DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*(BRU)P*(BRU)P*TP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*+UP*+UP*+UP*+UP*CP*+UP*AP*AP*GP*TP*CP*TP*TP*TP*+ UP*T)-3'), PROTEIN (DNA TOPOISOMERASE I), ... (4 entities in total) |
|---|---|
| Functional Keywords | topoisomerase i/dna), dna, topoisomerase i, isomerase-dna complex, isomerase/dna |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus, nucleolus P11387 |
| Total number of polymer chains | 3 |
| Total molecular weight | 84037.66 |
| Authors | Redinbo, M.R.,Stewart, L.,Kuhn, P.,Champoux, J.J.,Hol, W.G. (deposition date: 1998-01-29, release date: 1998-08-28, Last modification date: 2011-07-13) |
| Primary citation | Redinbo, M.R.,Stewart, L.,Kuhn, P.,Champoux, J.J.,Hol, W.G. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science, 279:1504-1513, 1998 PubMed: 9488644 (PDB entries with the same primary citation) DOI: 10.1126/science.279.5356.1504  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
