1A2E

CRYSTAL STRUCTURE OF A DOUBLE-STRANDED DNA DECAMER CONTAINING A CISPLATIN INTERSTRAND CROSS-LINK ADDUCT

1A2E の概要

• エントリーDOI: 10.2210/pdb1a2e/pdb
• 分子名称: DNA (5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*CP*GP*AP*GP*G)-3'), Cisplatin, ... (4 entities in total)
• 機能のキーワード: antitumor drug, cis-ddp, interstrand cross-link, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 6391.04

構造登録者

Coste, F.,Zelwer, C. (登録日: 1998-01-05, 公開日: 1999-04-12, 最終更新日: 2024-02-07)

• 主引用文献: Coste, F.,Malinge, J.M.,Serre, L.,Shepard, W.,Roth, M.,Leng, M.,Zelwer, C.; Crystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated site.; Nucleic Acids Res., 27:1837-1846, 1999; PubMed: 10101191; DOI: 10.1093/nar/27.8.1837

実験手法

X-RAY DIFFRACTION (1.63 Å)