1ZZZ
Trypsin inhibitors with rigid tripeptidyl aldehydes
Summary for 1ZZZ
Entry DOI | 10.2210/pdb1zzz/pdb |
Related | 1yyy |
Related PRD ID | PRD_000324 |
Descriptor | TRYPSIN, 2-{(3S)-3-[(benzylsulfonyl)amino]-2-oxopiperidin-1-yl}-N-{(2S)-1-[(3R)-1-carbamimidoylpiperidin-3-yl]-3-oxopropan-2-yl}acetamide, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 25286.51 |
Authors | Krishnan, R.,Zhang, E.,Hakansson, K.,Arni, R.K.,Tulinsky, A.,Lim-Wilby, M.S.L.,Levy, O.E.,Semple, J.E.,Brunck, T.K. (deposition date: 1998-06-02, release date: 1999-06-15, Last modification date: 2023-08-09) |
Primary citation | Krishnan, R.,Zhang, E.,Hakansson, K.,Arni, R.K.,Tulinsky, A.,Lim-Wilby, M.S.,Levy, O.E.,Semple, J.E.,Brunck, T.K. Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes. Biochemistry, 37:12094-12103, 1998 Cited by PubMed: 9724521DOI: 10.1021/bi980840e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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