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1ZSC

CARBONIC ANHYDRASE II MUTANT E117Q, HOLO FORM

Summary for 1ZSC
Entry DOI10.2210/pdb1zsc/pdb
DescriptorCARBONIC ANHYDRASE II, ZINC ION (3 entities in total)
Functional Keywordslyase, oxo-acid, acetylation, zinc, polymorphism, lyase (oxo-acid)
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P00918
Total number of polymer chains1
Total formula weight29222.29
Authors
Lesburg, C.A.,Christianson, D.W. (deposition date: 1996-01-09, release date: 1996-07-11, Last modification date: 2024-02-14)
Primary citationHuang, C.C.,Lesburg, C.A.,Kiefer, L.L.,Fierke, C.A.,Christianson, D.W.
Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II.
Biochemistry, 35:3439-3446, 1996
Cited by
PubMed: 8639494
DOI: 10.1021/bi9526692
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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