1ZP8
HIV Protease with inhibitor AB-2
Summary for 1ZP8
Entry DOI | 10.2210/pdb1zp8/pdb |
Descriptor | Pol polyprotein, [1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL (1R,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YLCARBAMATE (3 entities in total) |
Functional Keywords | protease, retroviral, hydrolase |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 1 |
Total formula weight | 11468.59 |
Authors | Brik, A.,Alexandratos, J.N.,Elder, J.H.,Olson, A.J.,Wlodawer, A.,Goodsell, D.S.,Wong, C.H. (deposition date: 2005-05-16, release date: 2005-06-21, Last modification date: 2023-08-23) |
Primary citation | Brik, A.,Alexandratos, J.,Lin, Y.C.,Elder, J.H.,Olson, A.J.,Wlodawer, A.,Goodsell, D.S.,Wong, C.H. 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors. Chembiochem, 6:1167-1169, 2005 Cited by PubMed: 15934050DOI: 10.1002/cbic.200500101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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