1ZEI

CROSS-LINKED B28 ASP INSULIN

Summary for 1ZEI
DescriptorINSULIN, M-CRESOL, ZINC ION, ... (5 entities in total)
Functional Keywordshormone, metabolic role, chemical activity, insulin mutant, cross-link, glucose metabolism, diabetes
Biological sourceSus scrofa (pig)
Cellular locationSecreted: P01315
Total number of polymer chains6
Total formula weight36993.87
Authors
Whittingham, J.L.,Edwards, E.J.,Antson, A.A.,Clarkson, J.M.,Dodson, G.G. (deposition date: 1998-07-14, release date: 1999-02-16, Last modification date: 2011-07-13)
Primary citationAntson, A.A.,Clarkson, J.M.,Dodson, G.G.,Edwards, D.J.,Whittingham, J.L.
Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37:11516-11523, 1998
PubMed: 9708987
DOI: 110.1021/bi980807s
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation
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PDB entries from 2021-06-23