1ZEF
structure of alkaline phosphatase from human placenta in complex with its uncompetitive inhibitor L-Phe
Summary for 1ZEF
Entry DOI | 10.2210/pdb1zef/pdb |
Related | 1EW2 1ZEB 1ZED |
Descriptor | Alkaline phosphatase, 2-acetamido-2-deoxy-beta-D-glucopyranose, PHENYLALANINE, ... (7 entities in total) |
Functional Keywords | alkaline phosphatase, uncompetitive inhibitor, intermediate state, l-phe, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor: P05187 |
Total number of polymer chains | 1 |
Total formula weight | 53856.10 |
Authors | Llinas, P.,Stura, E.A.,Menez, A.,Kiss, Z.,Stigbrand, T.,Millan, J.L.,Le Du, M.H. (deposition date: 2005-04-18, release date: 2005-06-28, Last modification date: 2020-07-29) |
Primary citation | Llinas, P.,Stura, E.A.,Menez, A.,Kiss, Z.,Stigbrand, T.,Millan, J.L.,Le Du, M.H. Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands. J.Mol.Biol., 350:441-451, 2005 Cited by PubMed: 15946677DOI: 10.1016/j.jmb.2005.04.068 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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