1Z7X

X-ray structure of human ribonuclease inhibitor complexed with ribonuclease I

Summary for 1Z7X

Entry DOI	10.2210/pdb1z7x/pdb
Descriptor	Ribonuclease I, Ribonuclease inhibitor, CITRIC ACID, ... (4 entities in total)
Functional Keywords	ribonuclease-inhibitor complex, leucine-rich repeat, enzyme-inhibitor complex, structural genomics, protein structure initiative, psi, cesg, center for eukaryotic structural genomics, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P07998 Cytoplasm: P13489
Total number of polymer chains	4
Total formula weight	129686.03
Authors	McCoy, J.G.,Johnson, R.J.,Raines, R.T.,Bitto, E.,Bingman, C.A.,Wesenberg, G.E.,Allard, S.T.M.,Phillips Jr., G.N.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2005-03-28, release date: 2005-06-21, Last modification date: 2023-08-23)
Primary citation	Johnson, R.J.,McCoy, J.G.,Bingman, C.A.,Phillips Jr., G.N.,Raines, R.T. Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. J.Mol.Biol., 368:434-449, 2007 Cited by PubMed: 17350650 DOI: 10.1016/j.jmb.2007.02.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation