1Z6F
Crystal structure of penicillin-binding protein 5 from E. coli in complex with a boronic acid inhibitor
Summary for 1Z6F
Entry DOI | 10.2210/pdb1z6f/pdb |
Related | 1NJ4 1NZO 1NZU 1SDN |
Descriptor | Penicillin-binding protein 5, N1-[(1R)-1-(DIHYDROXYBORYL)ETHYL]-N2-[(TERT-BUTOXYCARBONYL)-D-GAMMA-GLUTAMYL]-N6-[(BENZYLOXY)CARBONYL-L-LYSINAMIDE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | peptidoglycan synthesis, penicillin-binding protein, dd-carboxypeptidase, hydrolase, boronic acid |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 40513.65 |
Authors | Nicola, G.,Peddi, S.,Stefanova, M.,Nicholas, R.A.,Gutheil, W.G.,Davies, C. (deposition date: 2005-03-22, release date: 2005-06-21, Last modification date: 2023-08-23) |
Primary citation | Nicola, G.,Peddi, S.,Stefanova, M.,Nicholas, R.A.,Gutheil, W.G.,Davies, C. Crystal Structure of Escherichia coli Penicillin-Binding Protein 5 Bound to a Tripeptide Boronic Acid Inhibitor: A Role for Ser-110 in Deacylation. Biochemistry, 44:8207-8217, 2005 Cited by PubMed: 15938610DOI: 10.1021/bi0473004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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