1YPK
Thrombin Inhibitor Complex
Summary for 1YPK
| Entry DOI | 10.2210/pdb1ypk/pdb |
| Related | 1K1N |
| Related PRD ID | PRD_000628 |
| Descriptor | Prothrombin light chain, Prothrombin heavy chain, 10-mer peptide from Acety-Hirudin(54-65) sulfated, ... (5 entities in total) |
| Functional Keywords | thrombin, inhibitor complex, barrel, 6 stranded beta-sheet, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P28504 |
| Total number of polymer chains | 3 |
| Total formula weight | 34747.79 |
| Authors | Czodrowski, P.,Sotriffer, C.,Fokkens, J.,Heine, A.,Klebe, G. (deposition date: 2005-01-31, release date: 2006-01-17, Last modification date: 2024-11-06) |
| Primary citation | Fokkens, J.,Klebe, G. A Simple Protocol To Estimate Differences in Protein Binding Affinity for Enantiomers without Prior Resolution of Racemates Angew.Chem.Int.Ed.Engl., 45:985-989, 2006 Cited by PubMed: 16374786DOI: 10.1002/anie.200502302 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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