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1YPK

Thrombin Inhibitor Complex

Summary for 1YPK
Entry DOI10.2210/pdb1ypk/pdb
Related1K1N
Related PRD IDPRD_000628
DescriptorProthrombin light chain, Prothrombin heavy chain, 10-mer peptide from Acety-Hirudin(54-65) sulfated, ... (5 entities in total)
Functional Keywordsthrombin, inhibitor complex, barrel, 6 stranded beta-sheet, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P28504
Total number of polymer chains3
Total formula weight34747.79
Authors
Czodrowski, P.,Sotriffer, C.,Fokkens, J.,Heine, A.,Klebe, G. (deposition date: 2005-01-31, release date: 2006-01-17, Last modification date: 2024-11-06)
Primary citationFokkens, J.,Klebe, G.
A Simple Protocol To Estimate Differences in Protein Binding Affinity for Enantiomers without Prior Resolution of Racemates
Angew.Chem.Int.Ed.Engl., 45:985-989, 2006
Cited by
PubMed: 16374786
DOI: 10.1002/anie.200502302
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.78 Å)
Structure validation

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PDB entries from 2024-11-06

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