1YKI

The structure of E. coli nitroreductase bound with the antibiotic nitrofurazone

Summary for 1YKI

Entry DOI	10.2210/pdb1yki/pdb
Related	1ICR 1ICU 1ICV 1YLR 1YLU
Descriptor	Oxygen-insensitive NAD(P)H nitroreductase, FLAVIN MONONUCLEOTIDE, NITROFURAZONE, ... (6 entities in total)
Functional Keywords	oxidoreductase, oxygen-insensitive nad(p)h nitroreductase
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	98793.17
Authors	Race, P.R.,Lovering, A.L.,Green, R.M.,Ossor, A.,White, S.A.,Searle, P.F.,Wrighton, C.J.,Hyde, E.I. (deposition date: 2005-01-18, release date: 2005-02-08, Last modification date: 2023-08-23)
Primary citation	Race, P.R.,Lovering, A.L.,Green, R.M.,Ossor, A.,White, S.A.,Searle, P.F.,Wrighton, C.J.,Hyde, E.I. Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme. J.Biol.Chem., 280:13256-13264, 2005 Cited by PubMed: 15684426 DOI: 10.1074/jbc.M409652200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation