1YCI
Factor inhibiting HIF-1 alpha in complex with N-(carboxycarbonyl)-D-phenylalanine
Summary for 1YCI
Entry DOI | 10.2210/pdb1yci/pdb |
Related | 1H2K 1H2L 1H2M 1H2N |
Descriptor | Hypoxia-inducible factor 1 alpha inhibitor, FE (II) ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | fih, hif, dsbh, oxygenase, transcription, hypoxia, inhibitor 2-oxoglutarate, asparaginyl hydroxylase, hydroxylase n-(carboxycarbonyl)-d-phenylalanine, nofd, ndf, transcription regulator, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Potential): Q9NWT6 |
Total number of polymer chains | 1 |
Total formula weight | 41146.73 |
Authors | McDonough, M.A.,Schofield, C.J. (deposition date: 2004-12-22, release date: 2005-05-31, Last modification date: 2023-10-25) |
Primary citation | McDonough, M.A.,McNeill, L.A.,Tilliet, M.,Papamicael, C.A.,Chen, Q.Y.,Banerji, B.,Hewitson, K.S.,Schofield, C.J. Selective inhibition of factor inhibiting hypoxia-inducible factor J.Am.Chem.Soc., 127:7680-7681, 2005 Cited by PubMed: 15913349DOI: 10.1021/ja050841b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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