1XPU

Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-(3-formylphenylsulfanyl)-dihydrobicyclomycin (FPDB)

Summary for 1XPU

• Entry DOI: 10.2210/pdb1xpu/pdb
• Related: 1XPO 1XPR
• Descriptor: 5'-R(*CP*UP*CP*UP*CP*UP*CP*U)-3', Rho transcription termination factor, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: rho transcription termination factor; 5a-(3-formylphenylsulfanyl)-dihydrobicyclomycin (fpdb); atpgammas, transcription-rna complex, transcription/rna
• Biological source: Escherichia coli
• Total number of polymer chains: 12
• Total formula weight: 302311.25

Authors

Skordalakes, E.,Brogan, A.P.,Park, B.S.,Kohn, H.,Berger, J.M. (deposition date: 2004-10-09, release date: 2004-11-02, Last modification date: 2011-07-13)

• Primary citation: Skordalakes, E.,Brogan, A.P.,Park, B.S.,Kohn, H.,Berger, J.M.; Structural mechanism of inhibition of the rho transcription termination factor by the antibiotic bicyclomycin; Structure, 13:99-109, 2005; PubMed: 15642265; DOI: 10.1016/j.str.2004.10.013

Experimental method

X-RAY DIFFRACTION (3.05 Å)