1XPU
Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-(3-formylphenylsulfanyl)-dihydrobicyclomycin (FPDB)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (G, M, H, J, K...) | 5'-R(*CP*UP*CP*UP*CP*UP*CP*U)-3' | polymer | 8 | 2400.4 | 6 | |||
| 2 | G, H, I, J, K... (A, B, C, D, E...) | Rho transcription termination factor | polymer | 419 | 47070.2 | 6 | UniProt (P22869) Pfam (PF07498) Pfam (PF07497) Pfam (PF00006) UniProt (by SIFTS) (P0AG30) | Escherichia coli | |
| 3 | BA, M, O, R, U... (F, A, B, C, D...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 4 | AA, N, P, S, V... (E, A, B, C, D) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 6 | Chemie (AGS) | |||
| 5 | CA, Q, T, W, Z (F, B, C, D, E) | 5A-(3-FORMYLPHENYLSULFANYL)-DIHYDROBICYCLOMYCIN | non-polymer | 440.5 | 5 | Chemie (FPD) | |||
| 6 | DA, EA, FA, GA, HA... (G, H, A, B, C...) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 296823.6 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 5487.6 | |
| All* | Total formula weight | 302311.3 |
