1SHD

PEPTIDE INHIBITORS OF SRC SH3-SH2-PHOSPHOPROTEIN INTERACTIONS

Summary for 1SHD

• Entry DOI: 10.2210/pdb1shd/pdb
• Descriptor: C-SRC TYROSINE KINASE SH2 DOMAIN, TRKA RECEPTOR (3 entities in total)
• Functional Keywords: complex(transferase-peptide), complex(transferase-peptide) complex, complex(transferase/peptide)
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane: P12931
• Total number of polymer chains: 2
• Total formula weight: 13091.59

Authors

Gilmer, T.,Jordan, S. (deposition date: 1994-11-10, release date: 1995-01-26, Last modification date: 2012-02-22)

• Primary citation: Gilmer, T.,Rodriguez, M.,Jordan, S.,Crosby, R.,Alligood, K.,Green, M.,Kimery, M.,Wagner, C.,Kinder, D.,Charifson, P.,Hassel, A.M.,Willard, D.,Luther, M.,Rusnak, D.,Sternbach, D.D.,Mehrotra, M.,Peel, M.,Shampine, L.,Davis, R.,Robbins, J.,Patel, I.R.,Kassel, D.,Burkhart, W.,Moyer, M.,Bradshaw, T.,Berman, J.; Peptide inhibitors of src SH3-SH2-phosphoprotein interactions.; J.Biol.Chem., 269:31711-31719, 1994; PubMed: 7527393

Experimental method

X-RAY DIFFRACTION (2 Å)