1S39

CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2-aminoquinazolin-4(3H)-one

Summary for 1S39

• Entry DOI: 10.2210/pdb1s39/pdb
• Related: 1pud 1S38
• Descriptor: tRNA guanine transglycosylase, ZINC ION, 2-AMINOQUINAZOLIN-4(3H)-ONE, ... (4 entities in total)
• Functional Keywords: transferase
• Biological source: Zymomonas mobilis
• Total number of polymer chains: 1
• Total formula weight: 43152.27

Authors

Brenk, R.,Meyer, E.A.,Reuter, K.,Garcia, G.A.,Stubbs, M.T.,Klebe, G. (deposition date: 2004-01-12, release date: 2004-11-16, Last modification date: 2023-08-23)

• Primary citation: Meyer, E.A.,Furler, M.,Diederich, F.,Brenk, R.,Klebe, G.; Synthesis and In Vitro Evaluation of 2-Aminoquinazolin-4(3H)-one-Based Inhibitors for tRNA-Guanine Transglycosylase (TGT); HELV.CHIM.ACTA, 87:1333-1356, 2004

Experimental method

X-RAY DIFFRACTION (1.95 Å)